What is Methylsulfonylmethane (MSM)?

Wednesday, April 29, 2009 by Leslie Ellis
Most people cannot even pronounce Methylsulfonylmethane let alone know what it is or what it is for.  Let me explain this very important dietary supplement ingredient and why it matters to you.

Methylsulfonylmethane (MSM) is an ingredient used by many dietary supplement manufacturers in joint support products for people with arthritis.  It is a metabolite of dimethyl sulfoxide (DMSO) found in low amounts in fruits and vegetables and has a naturally high sulfur content.  Its antioxidant and anti-inflammatory properties may protect joint cartilage and plays a critical role in the elasticity and flexibility of the connective tissues of joints.

MSM has been historically used along with glucosamine and chondroitin to help alleviate joint pain and inflammation.  It can be used alone but is more typically used combined with other dietary supplement ingredients.

MSM Research
Researchers first started looking at the potential of MSM in the early 1960s but it wasn't until the 1980s and 90s when actual experiments were conducted.  As with many dietary supplement ingredients, results of clinical trials involving MSM have varied.  However, two new animal studies presented in April 2008, suggested further protective effects from MSM. 

Though MSM has not received as much attention as glucosamine and chondroitin, there has been recent heightened interest after the Arthritis Intervention Trial (GAIT) was published in 2006.

Evidence continues to grow showing that MSM is an effective ingredient for joint pain and inflammation due to osteoarthritis.  However, more research is needed.

If you are suffering from joint paint due to osteoarthritis, look for a high quality dietary supplement that includes all three ingredients:  MSM, glucosamine and chondroitin.  A liquid supplement is even better because it absorbs faster and is easier to swallow.  It should have at least 500 mg of MSM.  People allergic to sulfur should not take MSM.


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